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Column A vaccine could soon be here for one of the most devastating diseases on the planet

With malaria causing 627,000 deaths last year, there are high hopes for the first vaccine. But old-fashioned people power can also make a difference.

WORLDWIDE, MORE THAN 200 million people are infected with malaria every year, according to the World Health Organisation (WHO). Last year, malaria caused an estimated 627,000 deaths globally – mostly babies and young children in the poorest countries in Africa.

Malaria is truly a disease of poverty. It affects poor people disproportionately, as they tend to live in malaria-prone rural areas and in houses that offer little protection against mosquitoes. And malaria also fuels poverty, as it slows economic growth and worsens other disease burdens, particular HIV and Aids.

But there is good news on the malaria front. The number of malaria deaths has almost halved since 2002, according to the latest edition of the World Malaria Report. From 2000 to 2012, the number of reported malaria cases fell by 29 per cent, thanks to the mass distribution of mosquito nets, public awareness campaigns and quicker diagnosis methods, allowing for faster treatment.

In Zanzibar, for instance, the number of malaria cases has dropped dramatically in just eight years. In 2005, infection rates on the island stood at 40 per cent, but last year, it had managed to bring that number down to below 1 per cent. The Zanzibar government now aims to completely eradicate the disease by 2017. Whether it will achieve that will depend not just on political will or funding; it also depends on the parasite responsible for the disease.

Research into the disease is not keeping up with demand

Scientists point out that the current strategy is threatened by “the lack of insecticide classes available for public health and the emergence of resistance to the majority of existing insecticides.”

The market for public health pesticide products is seen as risky and too small to warrant commercial investment, compared to the market for agricultural insecticides. As a result, there have been no new active ingredients in malaria treatment available to the general public in over 30 years.

This is now set to change. Researchers in seven African countries are involved in testing the world’s first malaria vaccine, developed by British pharmaceutical company GlaxoSmithKline, with funding from the Bill and Melinda Gates Foundation. The company is seeking permission to sell the vaccine, provisionally known as RTS,S, after the largest ever drug test in Africa showed it reduced infection rates among children by half.

The company has promised that the vaccine will be sold at a price only marginally above production cost, and that the surplus will be reinvested in further research on malaria. And such research is needed, as GlaxoSmithKline itself has indicated that the vaccine does not have the hoped-for universal applicability and impact. (Bill & Melinda Gates)
Focusing on people, not just technology

But the solution need not come from technology alone. One of the key findings of decades of work by governments and development organisations is that simple measures work. Sleeping under insecticide treated nets, for instance, can reduce overall child mortality by 20 per cent. UNICEF estimates that bed nets can save approximately six children’s lives per year for every one thousand children sleeping under them.

There isn’t a ‘one size fits all’ method

Not getting bitten is obviously the best protection. Malaria is transmitted exclusively through the bites of Anopheles mosquitoes, which only bite at night or in the early morning. Transmission is more intense in Africa, where the mosquitoes’ lifespan is longer, and where they prefer to bite humans rather than animals.

Anopheles mosquitoes breed in water. Countries that have improved sanitation and reduced the occurrence of stagnant pools of water have managed to bring down infection rates, but Anopheles mosquitoes breed in such a variety of situations that it is practically impossible to remove suitable habitat for the mosquito. A better strategy, therefore, is to combine approaches based on our knowledge of the biology of the mosquito, the epidemiology of the parasite, and focused on changes in human behaviour.

Aid agencies have learned that there is not a “one size fits all” method for the fight against malaria. Unless local people, local authorities and local health care practitioners are involved in a coordinated way, and unless communities have access to trained, properly remunerated technical experts, the fight against malaria will not be won.

Bringing health systems to marginalised communities

In many developing countries, there simply are not enough health workers to respond to the needs of all rural communities. Programmes funded through overseas aid can make an enormous difference in such contexts, by bringing high-quality rapid diagnostic tests (RDTs) for malaria to marginalised people and by training frontline health workers to diagnose and treat patients for common diseases such as malaria, pneumonia and diarrhoea.

Aid agencies also help train people to diagnose and treat of malaria at home. Early diagnosis prevents deaths and should be a core part of any strategy to fight malaria. NGOs, therefore, typically bring together community volunteers, mothers, village leaders, traditional healers, and health workers to help them learn about, and take action against, malaria.

But knowledge is not the only major barrier to an effective anti-malaria strategy. For many poor communities, the medicines are simply too expensive, and the local health centres simply too far away, to be a real option. In many communities, aid agencies have helped set up village solidarity funds, funded by contributions from villagers and used to subsidise the transportation of young children with serious malaria or other health concerns.

A grass-roots approach to malaria control

What NGO work in countries like Zambia, Benin and Senegal is showing is that this approach is working. While many aid donors emphasise the importance of new drugs, the grass-roots approach to malaria control works with communities and families to help them recognise the symptoms of malaria and to ensure that even the poorest and most vulnerable members of society have access to medicines and bed nets.

Both approaches meet in the middle, through the coordination by national governments. And if anything, that is the vital ingredient for the international fight against malaria: the realisation that local governments and local solutions must always be at the heart of any programme aimed at ending disease, hunger and poverty.

Hans Zomer is the Director of Dóchas, the network of Ireland’s Development NGOs. Dóchas publishes the World’s Best News, a news service initiative from Irish NGOs which aims to highlight positive news stories from around the globe. Visit the World’s Best News on Facebook or worldsbestnews.tumblr.com for more information.

Read: Cases of malaria in Ireland rise for the third year in a row

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    Mute Ann Murphy
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    Sep 18th 2012, 8:53 PM

    its not as if the journal are the ones who wrote and staged the piece the are just reporting on it

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    Mute John Larkin
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    Sep 18th 2012, 9:30 PM

    No such thing as a bold child these days.

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    Mute Stephen Chinaski
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    Sep 18th 2012, 9:42 PM

    Probably because we have a richer understanding of the mind, instead of the binary good v. bad.

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    Mute Gary Guilfoyle
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    Sep 18th 2012, 9:43 PM

    It’s funny how instances of ADHD rise as you travel from west coast USA to East coast, it’s also funny how this trend corresponds to the ownership of games consoles and various technological gear kids are given these days. I’m not saying ADHD does not exist but it’s used to often as a get out Clause.

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    Mute Ann Murphy
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    Sep 18th 2012, 10:08 PM

    totally agree with u Gary there is such a thing as a bold child but its easier to say they have adhd rather than just saying their a brat

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    Mute Brighid Sheridan
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    Sep 18th 2012, 11:39 PM

    I don’t know about owning game consoles- my children have wii and ds consoles but the geography speaks volumes…

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    Mute John Tubridy
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    Sep 19th 2012, 12:36 AM

    My Da had a great cure for ADHD. A toe up the hole. Cured me every time.

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    Mute Pat Kirwan
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    Sep 19th 2012, 9:17 AM

    aka “mammy didn’t give me enough hugs syndrome”

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    Mute Ann Murphy
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    Sep 18th 2012, 10:10 PM

    true sometimes children are just bold and being a brat nothing else

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    Mute jonathan kerr
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    Sep 18th 2012, 10:48 PM

    adhd is just an excuse 4 parents not to put maners on their kids 4 being bold… no1 wants to tell their kids of anymore..

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    Mute Brighid Sheridan
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    Sep 18th 2012, 11:48 PM

    Jonathan that’s not true- myself and my husband try and discipline our children appropriately when necessary. When want to ensure that their actions don’t go unchecked. Simple manners like please and thank you- are just the beginning. Don’t tar all parents with the same brush…

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    Mute Brighid Sheridan
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    Sep 18th 2012, 11:37 PM

    Where was ADHD in the 70s and 80s?it seems all too prevalent nowadays. I do believe SOME parents misuse the condition to excuse “bad” behaviour. AND before I get red thumbed- I have 3 children-8,7 and 2. I do know what naughty vs good should be and when I as a parent should step up and take responsibility for my children’s behaviour and not blame a condition.

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    Mute Jambbie
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    Sep 18th 2012, 8:46 PM

    Should be ashamed of yourselves running this story. Many young kids including my own son have ADHD and I don’t take kindly to having it slagged off as is the case here. I’m all for a laugh and joke but not at some child’s expense. Shame on you. If it was a slur about skin colour, wheelchair bound people, mentally handicapped or blind people would you still run it.

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    Mute Stephen Chinaski
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    Sep 18th 2012, 9:38 PM

    I doubt the play makes fun of ADHD. The original ADHD and Asperger’s kids are in their twenties now. Things are becoming more tolerant, and diagnosed writers/actors are emerging. I wouldn’t worry.

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    Mute vv7k7Z3c
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    Sep 19th 2012, 7:01 AM

    Hi all,

    @Jambbie: With respect, I’m not sure what problem you have with this review. The show itself, which is part of this year’s Fringe festival, discusses ADHD and some of the reactions and misunderstandings surrounding the condition. It seems that there are some playful elements to the story but I don’t think that these try to poke fun at children or those with ADHD – far from it. In any case, TheJournal.ie didn’t write or stage the play – this is just a review of it.

    More generally, I’d like to point out that ADHD is a recognised behavioural condition that presents very real challenges to those who suffer from it and their families (see: http://www.apa.org/topics/adhd/index.aspx). It really isn’t helpful to suggest that children with ADHD are just “acting up”.

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    Mute Ger Copley
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    Sep 19th 2012, 7:24 AM

    my son was very bold and used to have at least half a dozen very bad tantrums every day,,, it was a nightmare,, doctor said he had adhd,,I didn’t agree,,I didn’t want to label my child just so his mother could get some extra allowance,,I changed his diet and made sure he got out for lots of exercise,, he was just a normal boy, with lots of energy that needed to be burnt off,, and u am aware that there are genuine cases, but kids are you easily labeled adhd,, their kids their supposed to be balls of energy and excitement,,

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    Mute Seany Mc Donagh
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    Sep 19th 2012, 5:26 AM

    Sounds like a good story . Could be a laugh. Wouldn’t mind seeing it for the craic.

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