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High blood pressure can double risk of Covid-19 death, study says

The new research was published today in the European Heart Journal.

PEOPLE WHO HAVE high blood pressure may be twice as likely to die from Covid-19 than those without the medical condition, according to a new study which included research from a team of experts at NUI Galway.

Scientists have said the risk is even greater among patients who are not taking medication to control hypertension.

The findings, reported in the European Heart Journal, are based on data from nearly 3,000 hospital patients in Wuhan, China.

However, the researchers said this result “should be interpreted cautiously”, adding that “patients should not discontinue or change their normal, antihypertensive treatment”.

Professor Fei Li, from Xijing Hospital in China and one of the study authors, said: “It is important that patients with high blood pressure realise that they are at increased risk of dying from Covid-19.

“They should take good care of themselves during this pandemic and they need more attention if they are infected with the coronavirus.”

A team of scientists, which also included researchers from the National University of Ireland Galway, looked at data from 2,866 patients admitted to hospital with Covid-19 between February 5-15.

Of these patients, 850 (29.5%) had a medical history of hypertension.

The team found 34 out of 850 patients (4%) with hypertension died after becoming infected with coronavirus, compared with 22 out of 2,027 patients without the condition (1.1%).

After adjustment for factors such as age, sex and other medical conditions, the researchers said those with high blood pressure had more than a two-fold increased risk of dying from Covid-19.

Among the patients who were not taking medication for hypertension, 11 out 140 (7.9%) died from coronavirus, compared with 23 out of 710 (3.2%) of those consuming the medicines.

The researchers then pooled data from three other studies involving nearly 2,300 patients to investigate the role played by RAAS inhibitors, a class of drugs commonly used to treat blood pressure, such as ACE inhibitors and ARBs, in Covid-19 death risk.

They found the risk of death to be lower among the patients who took RAAS inhibitors compared with those treated with other drugs such as beta blockers, calcium channel blockers (CCBs) or diuretics.

Professor Li said: “In contrast to our initial hypothesis, we found that RAAS inhibitors, such as ACE inhibitors or angiotensin receptor blockers, were not linked to an increased risk of dying from Covid-19 and, in fact, may be protective.

“Therefore, we suggest that patients should not discontinue or change their usual antihypertensive treatment unless instructed by a physician.”

A randomised clinical trial testing the effects of blood pressure medication on Covid-19 patients is set to run at the NUI Galway as part of the next steps in the research.

Newly appointed researchers will be working on the study at NUIG, including study co-author Professor Patrick W Serruys.

He said: “There are three remaining questions, and we hope our clinical trial in Ireland will answer the first two: what kind of medication should be given to Covid-19 patients with hypertension – RAAS inhibitors or non-RAAS inhibitors – and could these medications mitigate the risk of dying in these patients?

“The last question is whether or not RAAS inhibitors influence the risk of infection for Covid-19.”

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    Mute Glangan
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    Oct 23rd 2015, 7:17 AM

    €50 million is spent on the 1916 celebrations next year with this crisis going on. How about spending €1m instead and using the other €49m to provide accommodation to these people?

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    Mute Tordelback
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    Oct 23rd 2015, 7:34 AM

    I imagine Connolly would have agreed with you. But the answer will be ‘tourist revenue will greatly exceed…etc’. Not that this was a factor considered for the Dublin Web Summit, mind.

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    Mute bings
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    Oct 23rd 2015, 8:02 AM

    Why would the gov want to solve issues with homeless, hospitals, schools when they could spend millions on partying not that they require a reason to party.

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    Mute John Weldon
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    Oct 23rd 2015, 9:28 AM

    Millions goes into homelessness already, more money won’t make any difference. There should be one state backed homeless charity, say Peter McVerry, where people can donate and take out the huge levels of admin/management that comes with having 20 different organisations.

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    Mute Kevin Slater
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    Oct 23rd 2015, 9:58 AM

    Cherish all the children of the Republic. Action speaks louder

    75
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    Mute Wally Mooney
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    Oct 23rd 2015, 11:14 AM

    Homelessness is an inevitable result of 30+ years of neo liberal government policy where housing is treated as a profit center for the rentier elite and assorted vested interests in banking, law, auctioneering etc. As long as this continues, we will suffer the consequences as a society as demonstrated in the property bubble, inevitable crash, family home evictions, and the current soaring rack rents and homelessness crisis.

    There would be no scarcity of accommodation in Ireland if the government would play it’s proper role in ensuring the citizens had access to decent and affordable housing both rented and bought.
    This would require modifying the taxation and legal systems to encourage owner occupier home purchase and strongly discourage property speculation.

    In parallel the state needs to construct the necessary volumes of social housing and fundamentally reform the private rental sector with an immediate rent freeze and progressive rent reductions to affordable levels, banning economic evictions and ensuring security of tenure.

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    Mute Brian Deane
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    Oct 23rd 2015, 8:00 PM

    Better still, why not cut the funding to the self-interest quango lobby sector – the ones that like to pretend they have something to offer to Ireland.

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    Mute ÉireBlood
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    Oct 23rd 2015, 11:00 PM

    AAA, being against austerity is right, but you undo all that protest by being for immigration, either this country is for it’s people or it’s valuable, finite resources are for all, like you open-borders extremists like to say…IRELAND IS FOR ALL. There is only one path that hits the international predators, no to austerity, no to immigration. Ireland for it’s native people.

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    Mute Ross Harrison
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    Oct 23rd 2015, 11:35 PM

    So Wally it looks like you want the state to become a bigger landlord and that they should tax the working people in Ireland to pay for it. Social housing in this country has already created social disaster areas and you want want more of it! Out of interest if you were ever able to introduce your plan as outlined, when the accidental landlords can no longer afford the mortgage on their buy to let property (because you have reduced their rental income and imposed higher taxes so they have less take home pay). Did you consider that your plan would escalate the rental situation and make some of the landlord and renters worse off?

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    Mute Seán O'Sullivan
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    Oct 24th 2015, 2:20 PM

    well said one umbrella group Peter Verry for instance since it does so much. The way homelessness is being handled however many groups is with the usual incompetence we see, moved on from Merrion and th way they are otherwise moved from public view shows us how willing the gov are to make us seem in great recovery for the tourists

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    Mute Mike Cantwell
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    Oct 23rd 2015, 7:53 AM

    The lads and their dog may wait , there are 4600 Syrians etc and assorted Asylum Seekers getting preference and these will have the same rights as Irish people , in effect they will have more rights than these guys , take a bow Aodgain O Riordain and his PR people , the Irish Times and RTE

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    Mute Eamon Mac Gowan
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    Oct 23rd 2015, 8:54 AM

    @Mike Cantwell,
    Don’t forget their families who will arrive later, that’ll make it around 30,000. Also there will be far far more arriving next year.

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    Mute Kieran OKeeffe
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    Oct 23rd 2015, 10:25 AM

    Tough read..why cant that group of 3..almost a family..be treated as a family as opposed to childless single people..if the will was there to help then surely rent supplement x3 could be pooled in the short term to get them off the streets..of all the single people experiencing homelessness how many could genuinely house share with other singles?

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    Mute Donna Moss
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    Oct 23rd 2015, 6:59 AM

    How can the homeless crisis be solved? Who will take charge and make decisions ?

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    Mute Peter Slattery
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    Oct 23rd 2015, 8:20 AM

    Well Alan Kelly claims the government are ‘on top of it,’ so unless he’s a lying, two-faced, deceitful, incompetent piece of crap, there is no crisis.

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    Mute Bill Madden
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    Oct 23rd 2015, 8:46 AM

    Peter…
    Must have been great before this mob took power they obviously created the homelessness, and all the other ills in Irish society, but not to worry if you (foolishly ) elect SF/ independents….these homeless will dissappear in no time, because people will automatically stop substance abuse, and of course no one will buy an overpriced home (off the plans) they can’t afford. …no more hospital waiting lists (vested interest asside! ) “ordinary working people” love that term, won’t have to pay tax .Enda amd Joans huge pension will be capped at the average industrial wage, (of course the “permanent government will agree to all this, NOT) it will be Jerrys way or Brussels way…..we all know how that will go!! ….etc etc

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    Mute Peter Slattery
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    Oct 23rd 2015, 8:48 AM

    Defending the indefensible, Bill.

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    Mute Bill Madden
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    Oct 23rd 2015, 9:18 AM

    @ Peter… .not defending anything just pointing out that Nirvana is not at the end of the Opposition rainbow as so many people might think. This current lot said much of what the opposition are saying….remember in opposition it’s easy to point to the failure of the current Gov and you can promise ANYTHING FG/LAB promised the sun moon and stars but suddenly found the couldn’t or wouldn’t fulfil the promises, you can’t seriously think the opposition will keep their election promises just because it is SF etc.

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    Mute Peter Slattery
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    Oct 23rd 2015, 9:37 AM

    Nobody is suggesting that voting for the opposition will solve all problems. But voting this crowd again certainly wont solve anything. They’ve had four years (and counting) to prove they’ll make a difference, and they have come up not only short, but just as bad as the last crowd. Voting the same incompetent and corrupt gombeens into power time and time again is madness. You can be terrified of the opposition all you want, but the current government have been an abject failure when it comes to the homelessness crisis.

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    Mute Bill Madden
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    Oct 23rd 2015, 1:09 PM

    Peter…so let’s other incompetent, coruupt gombeens, instead, don’t forget it’s the permanent gov (civil service) who do most of the policy donkey work and is delivered by the ministers in the Dail (we don’t really think mike Noonan or Howlen actually work out a budget!) I wouldnt let some of them TDs wss my car…..PS the same CS are there now as we’re there during the crash and will be there when the next government is elected, and if anyone thinks SF /AAA etc will get rid of the CS the country would grind to a halt in 24 hours as TD would be lucky to get in the Dail DOOR let alone work!!!
    Put simply nothing really changes as the Civil Service is there since before independence

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    Mute Eamon Mac Gowan
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    Oct 23rd 2015, 8:33 AM

    It’s always the Irish who end up homeless, every foreigner gets far better treatment than our own people.

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    Mute Tap Solny
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    Oct 23rd 2015, 8:53 AM

    Eamon, blaming others is not a solution to any problem. You and Mike Cantwell have expressed similar sentiments. The similarities do not end there. Both of you have relatively new Facebook accounts, both of you have very few Facebook ‘friends’, both of you are Facebook friends with each other, both of you posted similar sentiments on the same day and within a relatively short period. The world is full of coincidences.

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    Mute Eamon Mac Gowan
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    Oct 23rd 2015, 9:00 AM

    @Tap Solny,
    Who made you facebook policeman, Mr Pat Lyons? As much as I am flattered to be accused as being the same person as Mike Cantwell it is alas untrue.
    I think you’ve too much time on your hands, Pat.

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    Mute Tap Solny
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    Oct 23rd 2015, 9:01 AM

    Good answer Eamon. That made me smile.

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    Mute Trish Loughman
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    Oct 23rd 2015, 10:06 AM

    Busted – lol.

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    Mute Mary Murphy
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    Oct 23rd 2015, 8:10 AM

    Is that the park Enda sat in last week for twenty minutes? This week the guards arrive to clear it?

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    Mute bings
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    Oct 23rd 2015, 8:38 AM

    Mary that’s last weeks news. Doesn’t Enda walk to work each morning so he can meet the real person going to work & talk to them. That is one way of finding out who is going to work & paying tax so he can spend it on crap.

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    Mute Freddie Fox
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    Oct 23rd 2015, 9:33 AM

    Yes indeed, they run our homeless out of the parks in case the tourists see them while they accommodate economic migrants in hotels.

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    Mute Elaynehb
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    Oct 23rd 2015, 8:49 AM

    beyond disgraceful. . These problems CAN be sorted but enda et Al chose to spend their time spinning yarns about how great they are, opening food banks and slighting other parties for things that either happened decades ago or in a jurisdiction that have nothing to do with them! It’d be funny if it wasn’t so terribly sad.

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    Mute Tap Solny
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    Oct 23rd 2015, 9:09 AM

    You previously posted disparaging remarks about Maria Cahill while expressing admiration for Pearse Doherty, a ‘politician’ that is a member of a party that lives in a mythological past that stretches back almost 1,000 years. I think I can understand where you are coming from.

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    Mute @mdmak33
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    Oct 23rd 2015, 9:28 AM

    not long to wait now thank god,right across the country people just want the GE, to wipe these two parties out ,along with ff,renua.never seen as many people interested in government behavior for a long time,and they are not impressed with the corruption, lies,and elitism.

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    Mute Davy Boy
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    Oct 23rd 2015, 8:01 AM

    Mike is right

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    Mute Philip Evans
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    Oct 23rd 2015, 12:39 PM

    how about putting some of the 1916 celebrations money in to fixing up all the empty council houses and giving them out the the people who need them … it won’t solve all of the issues but it would be a start … and I am sure that some people wouldn’t mind sharing a house until they get back on their feet

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    Mute Sean Duignan
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    Oct 23rd 2015, 2:09 PM

    I must say I find this homeless situation shameful to us as a nation. This situation should not be tolerated we need to look after our own people first. I raise money for the homeless constantly and recently completed 150 k cycle Dublin to Wexford for Peter Mc Verry Trust with many other greatly concerned people and still the situation gets worse. The waste and squandering of money by Government is disgusting and its our money!
    Charity begins at home!

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    Mute TommyJung
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    Oct 23rd 2015, 10:25 AM

    Lot of homeless people in Waterford too. All around the country actually.
    Even the homeless crisis has to be Dublin centric it seems.

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    Mute phil
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    Oct 23rd 2015, 11:28 AM

    This crisis needs to be tackled. I think drug testing should be used to determine who gets accomaded first.

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    Mute Ally O'Rourke
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    Oct 23rd 2015, 12:05 PM

    There’s a big problem in that homeless people who are down on their luck and who are non addicts are being bunched in with addicts, people with mental health problems and much more on floors of Merchants Quay, and in shared accommodation whereby they feel their lives are endangered by aggravated, near psychotic people who could do them serious harm. It’s dangerous and degrading and if you were sane before living through something like it, you won’t be when you spend much time in that environment, which is why most choose an alleyway with a sleeping bag instead, having known someone who went through it and left the country because of it, I can’t say I blame them doing this at all.

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    Mute keith cahill
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    Oct 24th 2015, 7:48 AM

    The opw and Dcc council own loads and loads of buildings around the city that are boarded up! for example the old driving licence building beside the 4 courts. can this not be transferred into a hostel for homeless people? also open up hostels for the homeless that charge people per night which the government covers completely. they would then be kept clean and safe

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    Mute throw9away
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    Oct 24th 2015, 11:44 AM

    lots of available social housing outside of Dublin… why can’t this be used?

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