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J&J vaccine to be approved today - but will supply issues hamper Ireland's progress?

The government has been told initial supplies in April and May will be smaller, with the majority of doses arriving in June.

THE EUROPEAN MEDICINES Agency is expected to give the green light to Johnson & Johnson’s one-dose Covid-19 vaccine today, but this latest ‘game-changer’ jab may also find it difficult to meet EU supply expectations next month.

Because of its one-dose regime and the fact that it can be stored at fridge temperatures – as well as high efficacy results in trials – governments across the EU have been eagerly awaiting its approval as they struggle to roll-out vaccinations on a large scale. 

This week HSE CEO Paul Reid said 3.8 million vaccine doses are expected to be delivered to Ireland in Q2, including the 600,000 Johnson & Johnson doses. 

The health service has been challenged in the roll-out by unexpected delivery shortfalls from all three manufacturers with EU-approved vaccines. Reid acknowledged that there have been up to 17 changes to vaccine plans so far due to these supply issues, as well as sequencing adjustments.

Now it appears an 18th change is on the horizon, as the bulk of Johnson & Johnson’s deliveries are now not expected to arrive in Ireland until June. 

This week Reuters reported that Johnson & Johnson has told the European Union it is facing supply issues that may impact on its ability to deliver the level of vaccines expected in the EU in the second quarter of this year.

It is reported that the company told the EU that issues with the supply vaccine ingredients and equipment means it was “under stress” to meet its goal of delivering 55 million doses by the end of June. An EU official said the company had stated it was not impossible to meet the goal, but it showed caution.

Speaking to RTÉ’s News at One yesterday, Tánaiste Leo Varadkar said he knows the “slippage on timelines” has been frustrating for people and “undermines confidence”.

Varadkar said the information the government has is that while Johnson & Johnson will be able to provide the 600,000 doses as promised in the second quarter of the year, a significant percentage will not arrive into the country until June. 

“Instead of it arriving in equal amounts in April, May and June, we now anticipate that there will be a relatively small amount arriving in April and then more in May and then the bulk of it in June,” he said. “So it’s the same amount, but it is a further delay unfortunately.”

In a statement in response to reports of supply issues, Johnson & Johnson said it has been “working directly with governments, health authorities and other companies to help end this pandemic”.

“To achieve our ambitious goals to deliver our Covid-19 vaccine candidate, we have focused on building a global supply network in parallel,” the firm said.

“We continue to start-up and activate new manufacturing sites as quickly as possible, such as the collaborations with Catalent, Reig Jofre and Sanofi Pasteur.

“As part of our commitment to transparency, we intend to provide another update to the European Commission and member states on our supply during our next meeting mid-March when the European Union Vaccine Steering Committee meets again.”

The company said it had reaffirmed its commitment, at the meeting with members of the EU vaccine steering committee last week, to deliver 200 million doses of the vaccine to the EU this year, starting in the second quarter. 

Thierry Breton, the EU industry commissioner, has said the bloc is now on target to receive 100 million doses in each of the next three months, and possible further hiccups have been “integrated” into the planning.

“I forced companies to have many, many (contingency) actions in case something could go wrong,” Breton said.

He added that reported production shortfalls in the United States by Johnson & Johnson would not impact the EU’s outlook.

“Do not believe that because one company has a problem that overall it will jeopardise the whole programme. This is why it’s good to have today – or let’s say tomorrow – hopefully four vaccines to go, and soon five,” he said.

What we know about the J&J vaccine

The Johnson and Johnson vaccine uses viral vector technology – the same approach as the Oxford/AstraZeneca vaccine. Viral vector vaccines use a modified version of a different virus – the vector – to deliver instructions to human cells.

The Johnson and Johnson vaccine uses a common cold-causing adenovirus which has been modified so it cannot replicate.

This ‘vector’ virus tells human cells to create the spike protein of the coronavirus. It prepares the immune system, training it to respond when it does come across SARS-CoV-2, the virus that causes Covid-19.

Unlike the two-dose vaccines we’re using currently, this vaccine only requires one dose. The vaccine can also be stored at fridge temperatures which opens it up to use in settings like GP surgeries, pharmacies and mass vaccination centres.

The manufacturer has said that its large Phase 3 trial included “significant representation” from those who are over the age of 60. The EMA, on approval of the vaccine, will provide guidance to member states on the use of this vaccine in specific age cohorts.

In large clinical trials, the vaccine’s efficacy against severe disease was 85.9% in the US, 81.7% in South Africa and 87.6% in Brazil. 

What the supply issues mean for Ireland

This vaccine was only due to make up about 15% of Ireland’s overall stocks in the second quarter of the year, so these shortfalls are not likely to have a catastrophic impact on the vaccination programme.

However the health service has been making plans based on the assumption that it would have access to large supplies in Q2 of a one-dose vaccine that could be used in community settings as it ramps up the programme. These supply issues may mean another reshuffle of the plans. 

Yesterday the Tánaiste said despite supply issues, the government still expects “roughly a million [doses] or just under” in April, 1.25 million May and 1.68 million June.

“This does come with a health warning that deliveries are out of our control and schedules change regularly,” he added.

When asked about the impact of potential shortages, the HSE said as the Johnson & Johnson vaccine has yet to receive EMA approval “we are awaiting confirmation of forecast delivery dates and volumes”.

“The HSE is putting plans in place in the event of EMA approval to ensure the swift distribution of the vaccine, if and when it is made available.”

- With reporting from AFP. 

 

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    Mute Derek Poutch
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    Jul 4th 2025, 11:40 AM

    If Mehole says they didn’t, they did.

    350
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    Mute jn
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    Jul 4th 2025, 11:33 AM

    fffg spin doctors in formula one mode with deflection tactics uni costs child care social welfare allowance kiddies never ending hospital housing mess with nothing to rent in west or south for low income, fffg with untrustable independents ducking and diving till 3 months long holidays, Keep ringing your local TD and ask the hard questions

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    Mute John McEvoy
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    Jul 4th 2025, 11:34 AM

    Why say something about something that probably got mentioned in person or print?

    195
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    Mute Louis Jacob
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    Jul 4th 2025, 11:41 AM

    @John McEvoy: That doesn’t matter anymore. Short news cycle. It’s day to day shenanigans with these guys. They just keep replacing one scandal with another one. And sadly; it works.

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    Mute John Paul
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    Jul 4th 2025, 12:30 PM

    @John McEvoy: Because they were asked the question.I always have to laugh at people who give out about politicians answering questions.If he didn’t answer the question you’d be even more annoyed.

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    Mute Elliot Alderson
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    Jul 4th 2025, 12:39 PM

    @John Paul: I have to laugh at gobdaws like you replying to everyone as if you are some superior being when all you are is a ‘Doe’ troll.

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    Mute John McEvoy
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    Jul 4th 2025, 12:52 PM

    @Elliot Alderson: yep. He’s got a response to almost every message sent. And in response to it I’ll say because politicians have this knack for avoiding giving answers to questions. Especially Simon Harris and Martin.

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    Mute John Paul
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    Jul 4th 2025, 1:30 PM

    @Elliot Alderson: na,you’re the gobdaw,you are following a party that will NEVER get into government and are obviously like the rest of the entitled layabouts in here that feel you are not getting enough free stuff.As I said,cry harder,I can’t hear you.

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    Mute Elliot Alderson
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    Jul 4th 2025, 2:00 PM

    @John Paul: As I told you before you lying sos I’m ex FF and follow no party blindly anymore. I’m also almost 60 and have worked all my life and never have taken anything from the state title. But you continue the auld Leobot concannonbot spin and propaganda to label anyone who might dare criticise Gov failures as following parties ‘that will NEVER get into Government’ and/or ‘entitled layouts’. Your the ‘entitled’ ‘layabout’ in here every day, who hypocritically whinges about whinging, who insults people and smears people, while claiming to have some moral superiority when your don’t. You are are nothing but Gov apologist ‘Doe’ troll.

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    Mute Elliot Alderson
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    Jul 4th 2025, 2:00 PM

    @Elliot Alderson: ‘anything from the state test’

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    Mute Mary BINTon
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    Jul 4th 2025, 2:45 PM

    @John McEvoy: They are so far behind with their workloads, nothing is getting done, everything Gov’t related is delayed, and they’re panicking, FF & FG have failed miserably since becoming one in 2016.

    151
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    Mute David Corrigan
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    Jul 4th 2025, 11:32 AM

    I wouldn’t believe the Lords word out of him. The man is a certifable liar and sleeveen.

    461
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    Mute barry williams
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    Jul 4th 2025, 11:35 AM

    @David Corrigan: 100% if he told you your name was David you would have to go home and check your birth cert just to make sure

    358
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    Mute David Corrigan
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    Jul 4th 2025, 12:19 PM

    @barry williams: Knowing our country is being managed by the likes of MM is gut wrenching. Completely clueless but what makes it worse is that he firmly believes he is a world leader and is doing a wonderful job.

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    Mute John Paul
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    Jul 4th 2025, 12:25 PM

    @David Corrigan: What makes it worse is the gobdaws in here like yourself think that Mary Lou is a world leader and would do a better job.cry harder till the next election and you’ll see that they will still be rejected.

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    Mute Elliot Alderson
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    Jul 4th 2025, 12:32 PM

    @John Paul: Your the gobdaw in here that gets triggered by any complaints of the Gov replying with your but, but SF bs. There is lots of people from all walks of life, think that this Gov conned the electorate to get votes and is an absolute joke at present, including even some that voted for FFG.

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    Mute John Paul
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    Jul 4th 2025, 12:42 PM

    @Elliot Alderson: No,I just correct people’s naivety that the opposition would be way better.Ive never said the government are doing a good job(go to ANY country and ask are their government doing a good job and they’ll tell you no)I don’t like this government,but I cannot stand any of the opposition.

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    Mute John Paul
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    Jul 4th 2025, 12:44 PM

    @Elliot Alderson: And the people spoke in the last election and they agree with me as well.The opposition were rejected rightfully again.This idea that the general public are thick and are sheep to keep on electing the same people is nonsense….They just don’t believe the opposition or trust them.

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    Mute D C
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    Jul 4th 2025, 1:03 PM

    @John Paul: what’s your ideas so or are you full of it?

    249
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    Mute John Paul
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    Jul 4th 2025, 1:27 PM

    @D C: I’ve explained….until a better opposition party comes along(I won’t hold my breath)this crowd(who I’m not a fan of but am happier that they are in government)will always get in.

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    Mute Gerry Lamont
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    Jul 4th 2025, 1:46 PM

    @David Corrigan: Unfortunately for the rest of us non FFG voters their supporters believe he walks on water.

    198
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    Mute David Corrigan
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    Jul 4th 2025, 1:59 PM

    @John Paul: Where did I say that? From what I see, none of them can do the job they are handsomely paid to do. That’s both sides of the house.
    You need to cool your jets also when people call out the fact your party are not up to the job. Getting all worked like that will only make you sick.

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    Mute Mary BINTon
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    Jul 4th 2025, 3:03 PM

    @John Paul: Your a dole fraudster, you get paid 3c per post by the trolling company you work for in cash.

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    Mute John Paul
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    Jul 4th 2025, 3:32 PM

    @Mary BINTon: lol,I make about 10/15 posts a day…check back on today for example.So I’m due 30c today.lol.im in my fifties and I’ve worked all my life and am doing very well for myself as an electrician.Its always the same nonsense thrown at anybody that talks about the opposition negatively….You’re a paid bot,try harder Mary.

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    Mute Mary BINTon
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    Jul 4th 2025, 3:46 PM

    @John Paul: It’s not my fault you don’t have the skills to get a real job, and I wouldn’t blame you taking the 3c in cash per post. Every little helps.

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    Mute Niall Binéad
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    Jul 5th 2025, 6:11 PM

    @John Paul: give it a rest JP, you’re full of it just like your boss MM!

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    Mute BL Music
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    Jul 4th 2025, 12:05 PM

    20 Jan 2025 — The State spent €1.43 billion on accommodation for asylum seekers and Ukrainian refugees during the first nine months of 2024, according to the latest figures.

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    Mute P. J.
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    Jul 4th 2025, 12:23 PM

    @BL Music:
    Money well spent if it riles up the 0.6 percenters!

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    Mute John Paul
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    Jul 4th 2025, 12:28 PM

    @P. J.: Exactly,it comes out in all of the whingers in here,the people who made really bad beds for themselves in a booming economy and like to blame everyone else for their mistakes and bad decisions.

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    Mute Elliot Alderson
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    Jul 4th 2025, 12:38 PM

    @John Paul: stop whinging about your perceived whinging you hypocrite.

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    Mute John Paul
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    Jul 4th 2025, 1:25 PM

    @Elliot Alderson: Try again in English.

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    Mute Declan Young
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    Jul 4th 2025, 1:25 PM

    @John Paul: who do you blame for your bad grammar?

    159
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    Mute John Purcell
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    Jul 4th 2025, 1:26 PM

    There doesn’t seem to be any talk of increasing tax bands / credits for the group of people that pay for everything so far

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    Mute Paddy C
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    Jul 4th 2025, 11:40 AM

    Can’t believe a word of it, they’re absolutely hopeless. It’s moreso annoying knowing there’s a shower of incompetent clowns running the country along the edge of a cliff with public finances not be handled correctly. No way the country would be able to withstand a recession with huge numbers entering the country and then all ending up on social welfare the deficit would be catastrophic.

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    Mute Paddy C
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    Jul 4th 2025, 11:43 AM

    not to mention even more numbers claiming rent allowance etc we’re on thin ice with they’re management, absolutely careless and reckless.

    163
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    Mute Jb Walshe
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    Jul 4th 2025, 1:51 PM

    Two habitual liars

    239
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    Mute Patrick Fitzgibbon
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    Jul 4th 2025, 11:53 AM

    Sad face ……happy face

    141
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    Mute Daniel Skelton
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    Jul 4th 2025, 12:28 PM

    Yes, we know they’re Gae and a Fail.

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    Mute Veil
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    Jul 4th 2025, 11:42 AM
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    Mute John Paul
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    Jul 4th 2025, 12:35 PM

    @Veil: You are not allowed to talk about social welfare fraud/disability fraud/council rent arrears/council housing wrecked.You are only allowed to whinge that not enough is handed to you for free and you’re not getting enough entitlements.

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    Mute Elliot Alderson
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    Jul 4th 2025, 12:41 PM

    @John Paul: oh look you nearly spammed everyone on the article, how classy of you.

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    Mute Thesaltyurchin
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    Jul 4th 2025, 1:17 PM

    @Veil: How many social welfare fraudsters are Irish you reckon? I’d say the entire rest of them apart from this lad! : ) kinda makes you wonder why it would only now be news tbh!

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    Mute John Paul
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    Jul 4th 2025, 1:21 PM

    @Elliot Alderson: I’m sure I included you a few times in the comment,probably why you are triggered.

    1
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    Mute Brian D'Arcy
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    Jul 4th 2025, 2:01 PM

    @John Paul: I have a disability and have no welfare payments, I bet not once in your life have you thought of how hard it is for people working with disabilities plus the fact that their financial costs are far higher than the ordinary worker,but is that attiyude of people who think only about themselves and ‘their’ money. In fact I’s imagine it sickens you that the state pays out for high-tech medication which the richest of the rich couldn’t afford throughout their life although I’d suspect you’d prefer to have them put down to save ‘your’ money.

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    Mute Veil
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    Jul 4th 2025, 2:29 PM

    @Thesaltyurchin: WRONG. An English woman was jailed recently for Illness benefit fraud. Don’t try to pull the racist card!

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    Mute Thesaltyurchin
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    Jul 4th 2025, 4:47 PM

    @Veil: Lol!… an ‘english’ woman you say? okay, so 2 people The rest all Irish we can agree? And this media site is picking up the trail eh? : )

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    Mute Ailbhe MacThomais
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    Jul 4th 2025, 11:41 AM

    Guaranteed the costs of asylum seekers and the other scamigrants won’t have any financial limits imposes as just to hurt the natives

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    Mute Veil
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    Jul 4th 2025, 11:43 AM
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    Mute John Paul
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    Jul 4th 2025, 12:31 PM

    @Ailbhe MacThomais: Pity the natives wouldn’t work to keep themselves warm and have personal responsibility for themselves.115K unemployed in a country with full employment.

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    Mute Elliot Alderson
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    Jul 4th 2025, 12:39 PM

    @John Paul: Pity you don’t stop trolling

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    Mute Shimo F
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    Jul 4th 2025, 12:57 PM

    @Veil: Crazy, should have been jailed or deported.

    11
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    Mute Ailbhe MacThomais
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    Jul 4th 2025, 4:30 PM

    @John Paul: I have seen friends,relatives and neighbours had to give up work due to taking care of elderly relatives as can’t afford nursing homes or employers get tax right off to employ migrants over native people.

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    Mute Joe Beirne
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    Jul 4th 2025, 11:33 AM

    Re the story below with respect to alleviating prisoners anxiety, should they not feel anxious going to prison, is that not the point of the deterrent?

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    Mute Brendan O'Brien
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    Jul 4th 2025, 11:45 AM

    @Joe Beirne: The loss of freedom is the punishment and the deterrent. Additional punishments are not supposed to be piled on top of that.

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    Mute Joe Beirne
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    Jul 4th 2025, 12:19 PM

    @Brendan O’Brien: Give over, you think they think about your feelings?

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    Mute Brian D'Arcy
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    Jul 4th 2025, 1:56 PM

    @Joe Beirne: He is right no matter how much you disagree with him. Instead of punsihing prisoners even further, their loss of freedom should be put to good use in helping them leave the prison and never come back by such simple things as teaching them to support themselves in the real world. What you seek is to keep them coming back to prison hence institutionalising them for life. Break the trend and you get them out the lifestyle that has brought them to that position, in fact the way things are, they are more likely to leave prison with a drug habit, even if they didn’t have one before.

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    Mute Joe Beirne
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    Jul 4th 2025, 2:33 PM

    @Brian D’Arcy: And we wonder why the country is the way it is.

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    Mute James King
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    Jul 4th 2025, 11:42 AM

    Social welfare is too high anyway. Huge amount of population doesn’t work in claims disability gets free housing .

    Increased payments should be for those who actually paid into the tax system over years and for X Y or Z reason lost their job

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    Mute Jimmy Kiely
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    Jul 4th 2025, 11:54 AM

    @James King: where are they getting the free houses, not a house anywhere in the country for reasonable rent. Plus we’re been told the affordable houses in Dublin are coming in around a half a million euros, what family can afford those prices and still have a life after.

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    Mute John Paul
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    Jul 4th 2025, 12:33 PM

    @Jimmy Kiely: Tens of thousands of council houses in this country are free….ie,people’pay’ their rent out of their dole.

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    Mute Elliot Alderson
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    Jul 4th 2025, 12:40 PM

    @John Paul: more rubbish troll

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    Mute Fiona Wyse
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    Jul 4th 2025, 1:02 PM

    @John Paul: correction it’s not their dole money it’s their wages…. this one makes me laugh every time whenever I hear it.

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    Mute thomas molloy
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    Jul 4th 2025, 11:47 AM

    Other countries are social engendering their work shy towards Ireland by restricting welfare payments. Overloaded lifeboats sinking springs to mind.

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    Mute Hunt Ley
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    Jul 4th 2025, 3:26 PM

    If asylum seekers can find work, why can job seekers not find same? No more money for chronically unemployed.

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    Mute S banter
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    Jul 5th 2025, 4:39 PM

    @Hunt Ley: a lot of home grown people are lazy and feel entitled. Even when they have contributed absolutely nothing, they demand everything.

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