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File photo. People strolling around the scenic Moshan by the East Lake in Wuhan Xinhua News Agency/PA Images

Wuhan study finds 40% of people with Covid were protected against future infection for at least nine months

The study in The Lancet said that mass vaccination programmes will be needed to reach herd immunity.

MASS VACCINATION WILL be needed for populations to reach herd immunity and prevent further resurgences of the pandemic, a new study based on data from Wuhan has found. 

Published in The Lancet, the study suggests that 6.9% of the population of the Chinese city had Covid-19 antibodies by April 2020. 

Of these, 40% of people had developed neutralising antibodies – which protect against future infection – and these remained stable for at least nine months.

Further, 82% of participants who had tested positive for Covid antbodies had not experienced any symptoms of the disease.

Wuhan was where the first cases of a “pneumonia of unknown origin” were reported in December 2019. 

The study involved sourcing data from over 9,000 participants. Blood samples were taken to test if antibodies were present in mid-April 2020, mid-June and between October and December. 

Of the 9,542 participants, 532 had antibodies against Covid-19. Four in five participants who had antibodies were asymptomatic cases. The study’s authors said this is much higher than other estimates reported around the world. They said this may be due to recall bias where a person is asked to report their own symptoms months later. 

Due to the relatively low presence of the disease among the population, researchers said that is unlikely that herd immunity will be achieved without effective mass vaccination campaigns.

Its lead author Dr Chen Wang, from the Chinese Academy of Medical Sciences and Peking Union Medical College, said: “Assessing the proportion of the population that have been infected with SARS-CoV-2 and who are immune is of utmost importance for determining effective prevention and control strategies to reduce the likelihood of future resurgence of the pandemic.

Given that individuals with mild infections might not seek medical care and that asymptomatic individuals are not usually screened, there may be large discrepancies between the reported Covid-19 cases, and actual infected cases, which has been proven by the experiences and data from other countries.

In a linked comment on the study, Professor Richard Strugnell and Dr Nancy Wang from the Doherty Institute in Australia said: “Given the relative paucity of neutralising antibodies through natural infection, the study by He and colleagues reinforces the need for effective Covid-19 vaccines in the population-level control of the disease.

“The extraordinary, rapid, and effective control measures implemented in Wuhan might have restricted the spread of the virus, but also reduced naturally-acquired herd immunity by truncating the development of sustained neutralising antibodies.”

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    Mute Cheryl Mellett
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    Jul 15th 2018, 8:41 PM

    Everyone wants the easy way out and a magic pill for everything these days but what kind of chemicals are we pumping into our bodies . That aside there are many benefits to going to a gym or exercising that a pill won’t give you like a social outlet, enjoyment, routine, positive affects on mental health, a sense of pride and achievement particularly for those involved in competitive sport and lots more. Exercise should be part of a normal healthy lifestyle not a chore. Find something you enjoy doing it’s not all about the gym or pounding the roads.

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    Mute Johnny Mason
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    Jul 15th 2018, 8:51 PM

    @Cheryl Mellett: I enjoying familiarizing myself to the couch every evening after a hard days graft so taking a pill to stay in shape might be a great solution for me

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    Mute Michael Bodycoach
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    Jul 15th 2018, 10:54 PM

    @Cheryl Mellett: Damn straight, the only true successes ever come from the time and effort you put in. Want to achieve something, avoid the short cuts, otherwise you achieve nothing! http://www.bodycoach.ie

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    Mute Gareth Cooney
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    Jul 15th 2018, 11:02 PM

    @Cheryl Mellett: Squash or Handball

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    Mute Phillip Maguire
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    Jul 15th 2018, 11:09 PM

    @Michael Bodycoach: Another witch doctor who has ‘the best plan’. Fitness coaches are the same as cult leaders, pyramid schemes, and palm readers, except arguably worse.

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    Mute Michael Bodycoach
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    Jul 16th 2018, 7:33 AM

    @Phillip Maguire: ha ha, you know nothing of what I do. I use science based techniques to get results. I do it the right way. I’m in no way affiliated to Mr Wicks

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    Mute classic
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    Jul 15th 2018, 8:54 PM

    Can’t beat hillwalking, better than any gym.

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    Mute Patrick J. O'Rourke
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    Jul 15th 2018, 9:17 PM

    @classic: absolutely. I don’t get why people would go and torture themselves in a big tin box with an intake of germs and other peoples sweat on a retail park when we have such a beautiful country. Nature heals the mind, delivers fitness as well as an education and tuning into the natural environment. Its free.

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    Mute Gary
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    Jul 15th 2018, 9:41 PM

    @Patrick J. O’Rourke: Because there are weights in the gym. Next question?

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    Mute Alan Currie
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    Jul 15th 2018, 10:43 PM

    @classic: doesn’t really do much for the upper body, but is a great fat burner

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    Mute Nucky
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    Jul 16th 2018, 12:00 AM

    @Alan Currie: until such a time as your body adapts and then it’s a plateau

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    Mute Alan Currie
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    Jul 16th 2018, 9:47 AM

    @Nucky: you can say that about any exercise though, a plateau isn’t some bad thing if you’re maintaining a strong balanced body and gotten to a position where you’re happy, you don’t have to keep building like some obsessive type.

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    Mute Radioska
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    Jul 15th 2018, 10:00 PM

    Long article. In short eat less, move more and don’t drink lots…. I’m a failure at the last one, that’s my personal downfall.

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    Mute Radioska
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    Jul 15th 2018, 10:25 PM

    @Radioska: Tell me about it, been on the piss for 2 weeks mate, feel like I’m just talkin to myself. Stops tomorrow for 4 days of liver self cleansing.

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    Mute Ken Maycock
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    Jul 15th 2018, 10:53 PM

    Don’t care how you train, you’ll NEVER outtrain a bad diet. I learned that one the hard way. Fix the diet first, and often its just the basics…. reasonable daily calorie deficit, right balance of protein/carbs/macros and you’re laughing. Exercise to tone and build muscle. Give it time, et voila!!

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    Mute Patrick Brophy
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    Jul 15th 2018, 10:32 PM

    While gyms are great places for doing high intensity exercise in short spats, I have taken to regular hill-walking again to stay in shape. Gyms can be somewhat soulless given that the exercise is all in doors. Plus, you are in the one spot for the entire time when exercising which can be monotonous and somewhat demotivating. Having said that, the exercise in a gym is far less time-consuming IF it is highly intensive.

    Outdoor exercise is much better as it gives the exerciser fresh natural air and breathtaking views (depending on the route). Plus, a shop or two along the way is a great way for short breaks and also a bottle of water to keep hydrated. It can also be very social if you have a partner or when you meet people en route.

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    Mute Alan Currie
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    Jul 15th 2018, 10:46 PM

    @Patrick Brophy: Plenty of free groups on meetup.com for anyone wanting to give it a go, with the safety of a group.

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    Mute Finn Faulkner
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    Jul 15th 2018, 10:42 PM

    Invest in a bike. Or Dublin Bike it. Commuting by bike and a weekend excursion of at least 60 minutes. That minimum will give you a noticeable benefit. Also trail or hill walking is good, but best done with others.

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    Mute Dave Harris
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    Jul 16th 2018, 12:32 AM

    @Finn Faulkner: Thats fine until you get hit by a car, a bus, a pothole, a car door. Cycling, unfortunately, is deadly.

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    Mute classic
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    Jul 16th 2018, 1:32 AM

    Just because you squat and lift weights in a gym doesn’t make you fit, it’s mostly superficial. Hillwalking make you very fit.

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    Mute SC
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    Jul 16th 2018, 7:17 AM

    I don’t have time for eating or drinking properly because I have two jobs and a long commute. If there was something that helped I’d take it. Any time I start exercising my periods stop which just causes more stress, less eating etc.

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    Mute James O Carroll
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    Jul 16th 2018, 2:45 PM

    i bet theres a couch potato out there who’s downing these pills and wondering why they are still fat

    1
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