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Blooms on the caster oil plant from which ricin can be made. caster oil plant image via Shutterstock

Here's what the poison sent to Barack Obama can do

The toxin ricin is feared – with good reason.

TWO RICIN-TAINTED letters have reportedly been sent to US government officials; a senator and President Barack Obama. Why is ricin such a feared substance? Here’s what we know about the toxin.

What it is: Ricin is a toxic protein that comes from the castor oil plant. Castor beans are not all that dangerous on their own because they are surrounded by an indigestible capsule.

How much is too much: It takes the pulp of about eight beans to kill an adult. If the protein is purified from the beans, a very small amount — less than 2 milligrams if injected — will kill a person. If eaten, about 2000 milligrams will kill someone.

Where it comes from: The waste from castor oil manufacturing, called waste mash, contains about 5% to 10% ricin by weight, but if it has been heated (which it usually is during the manufacturing process) the protein is no longer toxic.

To capture toxic ricin from castor beans, the protein needs to be separated out from the other plant proteins. There’s a patent that details how to do that, though it might not be all that effective. It probably takes a pretty good chemist to isolate the ricin protein in pure form that is still active.

If the ricin is going to be used as an inhalable poison, it needs to be adapted to a very small particle size to be effective, though it could also be dissolved in water and inhaled as a mist.

How it works: Ricin can kill you if it is inhaled, injected, or ingested. It is most potent when inhaled or injected into the body. Bulgarian writer Geogi Markov was murdered by the Bulgarian secret police by an injection of ricin disguised in an umbrella.

Ricin stops your cells from making proteins by attacking our protein-making factories, the ribosome. Proteins are an essential part of every part of your body.

How long does it take: Ricin isn’t the quickest-acting toxin. It can take up to a day after exposure for symptoms to show up, but it can kill you within three days. If you survive more than five days, you are likely to live.

What are the symptoms: Victims who ingest the protein get severe nausea and diarrhea. If it is inhaled, the patient will also have difficulty breathing and fluid will build up in the lungs.

They end up with an irregular heartbeat, low blood pressure, and seizures. This can last for up to a week. The patient can die of shock and multiple organ failure.

If you ingest the protein, treatment can usually reverse the symptoms and patients will survive, though they may suffer long-term organ damage. A man was poisoned with ricin in Las Vegas in February of 2008 and fell in to a coma for more than a month.

The Bulgarian writer Markov first showed a fever, was admitted to the hospital, and died three days later.

Pic of Georgi Markov and the tiny ‘bullet’ fired by an umbrella ‘gun’ at him – the pellet was found to contain ricin: PA Images

How is it treated: Treatment basically tries to minimise the effects of the symptoms of the poison. This could include ventilation to help breathing, giving fluids to help stave off dehydration, and giving medication to stop seizures and raise blood pressure.

The US and UK militaries have developed an antidote to ricin, but they haven’t been fully tested on humans. Researchers have also been trying to develop a vaccine for it.

Ricin is not all bad. Some researchers have been trying to use the toxin to kill cancer cells in the body. That is possible because the protein can be linked to a cancer-cell-specific antibody, which can go through the body without hurting normal cells.

- Jennifer Welsh

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    Mute Chris lynch
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    May 5th 2017, 1:44 PM

    Live a better – put away phone and get outside

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    Mute Chris lynch
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    May 5th 2017, 1:45 PM

    @Chris lynch: Live a better life*

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    Mute Rob Hunt
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    May 5th 2017, 1:45 PM

    Buy a 128GB storage phone, problem solved.

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    Mute Rob Hunt
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    May 5th 2017, 1:46 PM

    Genuine answer, if you have the google photos app you can just sett hat to back up your pics (though a little compressed if you’re on a free account) and let your phone automatically delete the device copies for you. Unless you’re mad for large apps that’s all that the majority of people need to do.

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    Mute Ronan BBurke
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    May 5th 2017, 1:47 PM

    On an iPhone, if you’re running out of space, attempt to rent a large HD movie from iTunes Store. It will tell you you have insufficient storage and will clear out temporary files etc.
    I can regularly regain about 1Gb from about 250Mb

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    Mute Graham McNamara
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    May 5th 2017, 2:18 PM

    @Ronan BBurke: went from 1.58gb to 4.24gb in 2 mins..cheers

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    Mute Ronan BBurke
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    May 5th 2017, 3:53 PM

    @Graham McNamara: Just be aware – if you try this with a movie that will fit on your phone… you’ll get charged. I usually pick something new and long – at least 3-4GB. Use it maybe once a month or so. Haven’t gotten charged. It doesn’t work if you click ‘buy movie’, only with ‘rent’.

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    Mute ⚡ Seánie ⚡
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    May 5th 2017, 2:44 PM

    Back in the 3210 days when you had to delete your text messages if you had over 50!

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    Mute Alan Cooke
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    May 5th 2017, 2:27 PM

    Just use your phone to annoy other posters on the journal.

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    Mute Derek
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    May 5th 2017, 2:02 PM

    On Android, going to Apps and clearly the cache will save reclaim considerable space, the browser along could have 300Mb – 1Gb, YouTube app also can have a large cache. Work your way down through the list clearing the cache in each as you go can help when short. Also delete games or ones you don’t often use, they tend to be 100Mb+ generally.

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