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Cutbacks 'causing stress' among parents of children with autism

New research shows that the levels of stress are higher when families have less access to autism services.

THE PARENTS OF children with autism have higher stress levels than parents of children without autism, or children who have other disabilities.

That is according to preliminary data from a study by NUI Galway’s Irish Centre for Autism and Neurodevelopmental Research (ICAN), which will be presented next week at a conference in the university city.

The research indicates cutbacks in services are having a real and measurable effect on parents’ wellbeing, ICAN said, as well as highlighting stress levels among parents of children with autism.

The Irish Society for Autism told TheJournal.ie:

We welcome any research that can help families with children with autism. It is important to highlight the need for services to be provided for people with Autism.  Research can highlight the deficiencies in services and this can lead to an improvement which benefits people with Autism and their families.

Stress

The study shows that levels of stress among parents of children with autism are higher when those families have less access to services.

Dr Geraldine Leader, Director of ICAN at NUI Galway, explained:

Our research is highlighting the negative impacts that cutbacks and inadequate service provision may have, not only on child outcomes, but also on the health and wellbeing of the parents.

This research included diaries, questionnaires, 24 hour blood pressure monitoring and also an analysis of the stress hormone cortisol. “We looked for the physical flags of stress, such as high blood pressure”, explained Dr Leader.

She said that their findings were not necessarily a surprise, and told TheJournal.ie that she hoped the research would help to bring the subject to the attention of the rest of the country, as stress can have “serious impacts” on those who suffer from it.

Perhaps none too surprisingly, parents of children of autism experience elevated levels of stress compared to parents of typically developing children. However, we were also able to show a correlation between increased stress among parents of children with autism who have less access to services and interventions.

Services and sleep

The preliminary results demonstrate that unmet services needs were a significant factor in the stress. Having a child with a greater number of service needs that were not being met (such as speech and language therapy, respite services) was associated with higher maternal blood pressure and higher parental reports of depressive symptoms and parenting stress, said ICAN.

The study also shows that sleep is an important factor. Child sleep problems and parental sleep quality were associated with maternal blood pressure, parenting stress, anxiety and depressive symptoms.

A group of 140 mothers, fathers and a control group of caregivers of typically-developing children were included in the study. The research was conducted by PhD student Ciara Foody under the supervision of Dr Leader and Professor Jack James.

It will be presented at the conference, Autism Spectrum Disorders: From Research to Practice, which will take place from 11-12 June. As well as keynote talks, it will also include a number of workshops where parents can get practical feedback on subjects such as mood, anxiety, DHS and the role medication; advocacy in Ireland; teaching key language skills; and managing challenging behaviour at home and in the classroom.

The event is being organised by ICAN in collaboration with the US science and advocacy group Autism Speaks, and runs from 11-12 June. For more information visit www.conference.ie

Read: Good news as autism help dog found alive and well>

Read: New study finds no link between vaccines and autism>

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9 Comments
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    Mute Tricia G
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    Nov 30th 2020, 5:09 PM

    The way the scientific community has worked to gather, sharing data etc., to try and get a solution to this problem is actually really inspiring.

    318
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    Mute John Brendan Mullen
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    Nov 30th 2020, 5:13 PM

    @Tricia G: Absolutely, no cause for suspicion.

    72
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    Mute Tricia G
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    Nov 30th 2020, 5:15 PM

    @John Brendan Mullen: Right……cos its just so likely that literally 1000s of members of the scientific community are conspiring to…. do what? Make you infertile? Have you grow a third ear? What? What’s their end game?

    Honestly, you must think everyone is just out to get you!

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    Mute michael
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    Nov 30th 2020, 5:17 PM

    @John Brendan Mullen: I really hope people like you are in the minority. We need a good take up rate to get our lives back to normal. Unless you really do like the rolling lockdowns.

    102
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    Mute Gavin Mckenna
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    Nov 30th 2020, 5:23 PM

    @John Brendan Mullen: Hat Foil Tin much?? Always one.

    62
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    Mute Kev
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    Nov 30th 2020, 5:24 PM

    @michael: you would be surprised of the amount of people who are unfortunately sceptical of the vaccine. This is the problem with social media, it gives people a platform to spread information without any factual evidence to back it up.

    54
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    Mute artur filip
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    Nov 30th 2020, 6:14 PM

    @Kev:The Virus Won’t Stop Evolving When the Vaccine Arrives
    The coronavirus is not a shape shifter like the flu virus, but it could become vaccine resistant over time.
    https://www.nytimes.com/2020/11/27/science/covid-vaccine-virus-resistance.html?fbclid=IwAR22o94Fe-Co6Q2YbxyJ0UOuL8MSHeBjVJ7GxyagDgQJ7opqS-k4PLAZ4h4

    4
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:24 PM

    @Tricia G: not at all, I just don’t want to be a human guinea pig for a vaccine that has not been proven. Also, I don’t see the point in taking a vaccine for such a benign virus. I’ve has it and while I wouldn’t recommend it, I’d choose for another dose of corona before a root canal treatment

    14
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:27 PM

    @michael: i don’t like lockdown but I have enough sense to do my own research and what I have found in the official government statistics is a lower monthly mortality rate for every month of 2020, excluding April, compared to the same month over the previous 5 years

    12
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:29 PM

    @michael: what we really need is for people to stand up for their basic civil and human rights

    10
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:32 PM

    @Gavin Mckenna: hahaha, you have won me over with the precision and depth of your case, head case

    9
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    Mute Faded79
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    Nov 30th 2020, 6:37 PM

    @Tricia G: I’ve no issue with vaccinations but this is yet to be peer reviewed. We have only press releases but already we are talking about rolling it out. The scientific community needs to come back together to your point and verify the data now as there’s a lot of questions to answer. The british medical journal highlighted as such yesterday

    14
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:42 PM

    @Kev: same applies to the mainstream media

    5
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    Mute Watchful Axe
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    Nov 30th 2020, 8:49 PM

    @michael: It could still come back in from the likes of Brazil at a later date, not sure how distribution of a -70 degree vaccine will get on in those countries. But it’s got to be very mild after everyone has their bodies ‘trained’. It’ll only be the antivaxers left to get the full wack with a naive immune systems.

    3
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    Mute John Purcell
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    Nov 30th 2020, 8:53 PM

    @John Brendan Mullen: how are you being a quinea pig by taking the vaccine do tell us

    4
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    Mute Dave Hammond
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    Nov 30th 2020, 8:54 PM

    @John Brendan Mullen: yes John – and here’s a heads up for you
    \
    ‘just because you are paranoid doesn’t mean they are not out to get you’.

    get some fresh air….

    5
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    Mute Fabio Dillon
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    Nov 30th 2020, 11:11 PM

    @John Brendan Mullen: melt of a human

    7
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    Mute John Brendan Mullen
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    Nov 30th 2020, 11:26 PM

    @John Purcell: as I said, I won’t be taking their vaccine

    3
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    Mute David Jordan
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    Dec 1st 2020, 2:06 AM

    @artur filip: the brilliant advantage of mRNA vaccines is the ability to rapidly change the mRNA in the vaccine to match any future virus mutations without having to go back to designing the vaccine from scratch.

    7
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    Mute David Jordan
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    Dec 1st 2020, 2:21 AM

    @Faded79: “ve no issue with vaccinations but this is yet to be peer reviewed.”

    No, vaccines are being peer reviewed e.g.

    Anderson, et al., 2020. Safety and immunogenicity of SARS-CoV-2 mRNA-1273 vaccine in older adults. New England Journal of Medicine. 10.1056/NEJMoa2028436

    Approval by regulators is another layer of peer review.

    Also, the first batches of vaccine will be given to medical workers and care home staff, it will be in short supply. The next group to get the vaccine will be high risk groups, elderly in care homes, people with pre-existing conditions e.g. Cystic Fibrous, COPD, severe Asthma etc.

    As the vaccine is rolled out gradually over the next year, I think confidence will increase as people see there’s no adverse advents. The last phase will be general vaccination, children will be last. By then we will have lots of data on the safety of the vaccines and confidence will be higher then now.

    8
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    Mute Ned Gerblansky
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    Nov 30th 2020, 5:21 PM

    Just got off the phone with George Soros and Bill Gates, they said they are very worried that a few lads who dropped out before the junior cert are after uncovering their scheme.

    216
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    Mute William King
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    Nov 30th 2020, 6:15 PM

    @Ned Gerblansky: Brilliant

    22
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    Mute Spongetron
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    Nov 30th 2020, 6:28 PM

    @Ned Gerblansky: sums up every comment section on the subject

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    Mute EFitz66
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    Nov 30th 2020, 7:52 PM

    @Ned Gerblansky: Brilliant

    6
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    Mute John Kinsella
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    Nov 30th 2020, 5:05 PM

    Sign me up..

    145
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    Mute John Brendan Mullen
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    Nov 30th 2020, 5:08 PM

    @John Kinsella: I delegate you to take their vaccine on my behalf

    57
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    Mute Evan
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    Nov 30th 2020, 5:21 PM

    @John Brendan Mullen: or you could take the wild decision of making your own decision and letting others make theirs.

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    Mute John Kinsella
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    Nov 30th 2020, 5:47 PM

    @John Brendan Mullen: You are on!

    3
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:27 PM

    @Evan: i won’t be taking their vaccine

    10
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    Mute Evan
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    Nov 30th 2020, 6:31 PM

    @John Brendan Mullen: as is your right. It won’t be compulsory so I have no idea why you and your ilk have to keep shouting it from the rooftops. Nobody is going to force you. I didn’t take sugar in my tea this morning, I didn’t feel compelled to go around informing everyone I met though.

    37
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:44 PM

    @Evan: I’m just having a wee giggle at all you concerned citizens, this lockdown madness would be a lot worse if I didn’t have you guys to amuse me

    7
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    Mute Fabio Dillon
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    Nov 30th 2020, 11:12 PM

    @John Brendan Mullen: h

    1
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    Mute Fabio Dillon
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    Nov 30th 2020, 11:12 PM

    @John Brendan Mullen: hopefully you will be stopped from attending events and travelling. Good luck with your boring existence.

    9
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    Mute Gerry Murphy
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    Nov 30th 2020, 5:14 PM

    Irish government has indemnified drug companies against any liability arising from complications with the vaccine. Why?

    63
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    Mute Tricia G
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    Nov 30th 2020, 5:17 PM

    @Gerry Murphy: Because there isn’t a single modern medicine that is 100% safe.

    It’s a risk-cost benefit analysis.

    There are always people that will have a bad reaction, but in the overall scheme of things, many millions will be helped.

    125
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:45 PM

    @Gerry Murphy: ask ned gerblansky, he’s the clever clown in here

    6
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    Mute Gerry Murphy
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    Nov 30th 2020, 5:17 PM

    The drug companies have gov.indemnity against liability in case of problems with vaccine.

    39
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    Mute Tricia G
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    Nov 30th 2020, 5:18 PM

    @Gerry Murphy: You realise that’s not some massive conspiracy, right?

    83
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    Mute Arch Angel
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    Dec 1st 2020, 9:34 AM

    @Gerry Murphy: We know every scientist has been working on a vaccine non stop since the beginning of the year. Yet despit this people with little or no qualifications still believe they know more than the combined weight of the worlds scientists who have reviewed and checked each others work. Literally, millions of extremely well qualified people in almost every country, sharing data and checking it, but one keyboard warrior thinks he knows better. The mind boggles.

    5
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    Mute snotser
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    Nov 30th 2020, 5:38 PM

    Well I won’t be taken it.

    30
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    Mute David Clements
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    Nov 30th 2020, 5:53 PM

    @snotser: it doesn’t work in pigs. Or pillocks

    65
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    Mute Brian Ó Dálaigh
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    Nov 30th 2020, 5:54 PM

    @snotser: well, soon you’ll not be allowed to get on a plane without a vaccine (Qantas and several minor airlines have already announced this, with more to follow suit), so that will be your holliers in the Costas gone.

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    Mute artur filip
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    Nov 30th 2020, 6:04 PM
    8
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    Mute snotser
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    Nov 30th 2020, 6:17 PM

    @David Clements: that’s exactly why I’m not taking it,I’ll be bacon by then

    7
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    Mute Michael Byrne
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    Nov 30th 2020, 6:23 PM

    @artur filip: Travel agents do nothing these days. They’d be nothing without airlines. Just wait till more airlines go with this, watch the agencies change their tune. Why anyone doesn’t book their own flights and hotel is beyond me….it’s much cheaper.

    19
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    Mute Brian Ó Dálaigh
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    Nov 30th 2020, 6:27 PM

    @artur filip: travel agencies are largely redundant. Meanwhile, United Airlines, Emirates, Gulf, Aeroflot, and Delta are all looking like they will also being in the same requirement. It looks like, before long, that travel agency will have no customers.

    16
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    Mute John Brendan Mullen
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    Nov 30th 2020, 6:46 PM

    @David Clements: so you’ll have to give it a miss then. ? Ahh, god bless

    2
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 5:19 PM

    It’s important to highlight that older vunerable people are not the main people that the vaccine is tested on.
    The real test of success is when it’s rolled out to those this group.
    30,000 volunteers doesn’t represent what efficiency we’ll get on a million older and vunerable people in Ireland.
    https://www.healthline.com/health-news/older-adults-are-more-at-risk-for-covid-19-so-why-dont-vaccine-trials-include-them

    So hold the horses on the idea the vaccine can achieve such high efficiency.
    The approval would be given even if 50% efficient.
    Flu vaccine varies every year from 20% to 60%, there’s a few strains of flu that causes this.
    Mounting the immune response required in older adults is a long standing challenge in human Vaccines .

    18
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    Mute Tricia G
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    Nov 30th 2020, 5:24 PM

    @Rory Mac Daibhéid: The moderna trial had 7000 people over the age of 65.

    64
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 5:37 PM

    @Tricia G: I tried to get the numbers of idler adults and all I could find was that in general older adults are under represented.
    Have you the data?

    In Ireland the median age of deaths for covid is 83 and mean age 81.

    I’m very skeptical a vaccine will stimulate an immune response in those that need it most.

    I’ve no doubt that a vaccine can work in younger healthier volunteers but in general covid doesn’t affect them, the vaccine trials say it’s tested on people that haven’t had covid . But they don’t test for existing immunity or T or B cells so when they say success it’s based on exposure and nobody is testing full existing Immunity.

    I don’t see how the vaccine can have high success in the people that are over represented in the covid deaths statisics.

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    Mute Tricia G
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    Nov 30th 2020, 5:42 PM

    @Rory Mac Daibhéid: I got the information from the article you posted…….

    It details multiple trials, first one is the moderna one. The details of the phase three trial state “This included more than 7,000 people over the age of 65 and more than 5,000 younger people with chronic conditions…”

    It also links to the Moderna announcement from Oct 22nd.

    22
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    Mute ▪️
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    Nov 30th 2020, 5:43 PM

    @Rory Mac Daibhéid: It’s not rocket science, Rory, or at least this part isn’t.

    The more non-vulnerable people that are immunised, the less they will spread the disease throughout the community, the less Covid reaches the old and vulnerable.

    Even if older people don’t have a strong immune response to the vaccine (not suggested by the data so far) then it’ll still have a huge effect on the pandemic because they’ll have less chances of contracting it from other people in their daily lives.

    26
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 5:47 PM

    @▪️:
    My statement didn’t suggest a vaccine won’t have an effect.

    I’m very skeptical we’ll have a strong Immune response that prevents deaths is the majority of people in Ireland who covid killed. Over 80′s.
    If less covid is in circulation due to a vaccine it could indirectly achieve that.

    5
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 5:50 PM

    @Tricia G: They discovered that in studies registered between October 2019 and June 2020, over 50 percent of COVID-19 clinical trials and vaccine trials excluded people over 65.”
    ? Where did you get the information that 7000 over 65 in Moderns Trial?

    When you get 100,000 over 80 in a trial you’ll see how successful it is.

    I think all the people in Trials that are older like in every country are not exposing themselves to infection so all the cases of infection in younger people doesn’t seem like evidence to me.

    3
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 5:53 PM

    @Tricia G: Our concern is more than theoretical. Even without stated age-based exclusions, several recently published clinical trials of COVID-19 treatments had young age ranges, such as 1 recent study4 with a median age of only 40 years, meaning there would be no or few participants over age 75.”

    That’s my concern and nobody is addressing it.

    3
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    Mute Tricia G
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    Nov 30th 2020, 5:57 PM

    @Rory Mac Daibhéid: Eh…. There were no studies in 2019…

    Also, please read down the page in the article YOU POSTED! Under the section COVID-19 vaccines.

    And don’t think I didn’t notice you’re moving the goalposts.

    Your point was older people were excluded from the 30,000 cited. That’s not true as per Moderna’s release as of Oct 22nd 2020 (all linked in your article).

    No one disputes that those most at risk are the elderly, but a phase 3 trial with 7000 over 65 and still with an immunity in the 90% range is very good.

    23
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    Mute Tricia G
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    Nov 30th 2020, 5:58 PM
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    Mute Tricia G
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    Nov 30th 2020, 6:03 PM

    @Rory Mac Daibhéid: BTW, after reviewing the press release, I read the article in the New England Journal of Medicine FROM Sept 29th 2020 detailing a trial involving 55-70 and 70+

    I suggest you go check it out.

    11
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    Mute Spongetron
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    Nov 30th 2020, 6:06 PM

    @Rory Mac Daibhéid: dig up Rory

    6
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 6:07 PM

    @Tricia G: I’m not moving any goalposts.
    Thanks for the link you’ve sent me the information I was looking for. I checked for This information and couldn’t find it.
    That’s (your Link) is more reassuring than what I’ve seen so far.

    To achieve high efficiency in such age groups in main mark of success to me.

    3
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 6:23 PM

    @Tricia G: I suggest people be honest also, the vaccine has not shown it will save the lives of the mean person who died of Covid. That’s a 83 year with 2 underlying conditions. There’s a massive difference between over 65 and over 75.
    The concern I have is this vaccine is still it’s not shown to work in over 75 year olds with underlying conditions.
    Thats who needs Protection from covid.
    The data from HSPC gives the details of those deaths.

    Which leaves me with same question.

    Which can only be answered if they rollout out the vaccine to the most vunerable.

    Stage 3 trail is not evidence in my opinion of efficiency.

    It’s a good result but biased and skewed.
    Let’s see what happens when the do the real World trail.

    It’s likely to protect the over 75s is to stop them getting covid still for the foreseeable future.

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    Mute Joeohah
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    Nov 30th 2020, 6:33 PM

    @Rory Mac Daibhéid: 

    More importantly they have not said if it stops transmission,  with the Oxford vaccine  they reported that they think it may have some impact!

    99+ of the world population have not gotten ill from SARS CoV2 – 7.8billion divided by those tested positive 63million, 40milllion recovered. the promotion for these vaccines is less than that. If these vaccines don’t stop transmission then hopefully they will work on older people, if not then then they may be a great Placebo!

    In Nigeria last time I checked, about two weeks ago,1163 died from C19 out of 203million. Lagos city has a population of over 14million, 3 times the population of Ireland! Proof if ever there was that C19 impacts hardest on older people -life expectancy is 57 in Nigeria and they only have 350 ICU beds!

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    Mute Joeohah
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    Nov 30th 2020, 6:41 PM

    @Rory Mac Daibhéid:
    Your not allowed ask questions, without question you must believe in the consensus belief science, otherwise you may be asked to resign and will be classified as an outlier and anti vaxxer!

    9
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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 6:48 PM

    @Joeohah: it’s doesn’t stop transmission. It doesn’t stop infection and it’s meant to stop illness.
    With covid your immune system stops illness when you’re young.
    When you’re older your immune response is lessened hence the data on who covid19 affects most.

    I think vitamin D and finding medical treatments for respiratory illnesses would save more lives than the vaccine directly.

    Indirectly I think it might save lives but I’m uncertain.
    We should treat this like we do a bad flu season and also be realistic that flu vaccine never eradicates flu.
    I’m skeptical until proven otherwise, nothing done to date proves otherwise.

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    Mute Rory Mac Daibhéid
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    Nov 30th 2020, 7:05 PM

    @Spongetron: everyone should dig into the vaccine expectations especially as it’s affects so many.
    I rather I didn’t have to hear these false claims and misleading things in the media.
    Outright lies and fabrication from AstraZeneca’s trial already. Basically 62% efficiency in under and then they pretend they had 90 % , which was under 55s, and the only reason was a dosing error!
    Media is driven a false narrative and absolute shambles about this magic bullet vaccine.
    It’s another flu vaccine, let’s hope it’s better than the 20% efficiency which is still considered a success for flu vaccine years.

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    Nov 30th 2020, 7:10 PM

    @Rory Mac Daibhéid:
    “your just another anti vaxxer!” “do you not care if people die!” Remember 88 people die every day in Ireland and yesterday the HSE said that there are 85% fewer people are on trollies compared to this time last year!

    They will be able to claim the vaccine worked in the summer and later they can say that 90% are not ill which is already the case.
    Let’s hope it does work, even as a placebo!
    Remember the swine flu vaccine farce, it was never needed.

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    Nov 30th 2020, 7:32 PM

    @Joeohah: you get a lot of abuse if you ask questions or the death shame cancel culture.
    I don’t think any rational and logical debate is allowed in this pandemic.

    What people should remember is the people in charge decided in March they won’t Protect anyone over 80 in a nursing home when they went ahead untested all patients from ICU , sent them to nursing homes, allowed people in nursing homes to die, no access to ICU or medical care, given sedatives only and nobody got near them. So we’d over 60% of the deaths here back in the first wave.
    The Government and NPHET and the HSE decided these deaths where not to be important as they believed we’d have tens of thousands dying.
    Every model was wrong.

    Now we’re to believe they want to save lives.

    The vaccine won’t work on the immune system on the majority of the people that died of Covid in my opinion.
    In the general population it will work, what’s driving that will be a mix of things though.
    Boosting the immune system and changing how institutional care and elder care in the country is the main way they could save lives.

    Professor Luke on Newstalk said Pharma wouldn’t lie about the efficiency, but Astra Zenca lied so much there in trouble for it!
    Will Professor Luke correct that in the media now?? https://www.nytimes.com/2020/11/25/business/coronavirus-vaccine-astrazeneca-oxford.html

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    Nov 30th 2020, 7:55 PM

    @Rory Mac Daibhéid:
    Yes, and still no inquiry into the nursing home deaths at least Sweden admitted there mistakes, thus they learned from it!
    I can’t post links!

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    Nov 30th 2020, 7:59 PM

    @Rory Mac Daibhéid: Rory, your comments are all over the shop. There’s so much wrong in each of them it’s actually too time consuming to pick out each point.

    We can go one by one if you like. Let’s start with one or two.

    When did AstraZeneca “lie” about results? If you think they lied a) you don’t understand the story and b) Oxford/AZ informed the regulator and got the go-ahead for the trial design after they realised what they’d messed up. All above board – where was the “lie”?

    How aren’t phase 3 trials proof of efficacy (the word is efficacy, not efficiency like you keep saying, that’s something completely different)? That’s exactly what Phase III trials are designed for.

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    Nov 30th 2020, 8:01 PM

    @Rory Mac Daibhéid: 20% is an extremely low figure for flu vaccine efficacy, just to clarify. Most estimates put the efficacy between 30-60%, varies by year, but even low efficacy will impact the spread of a virus when you scale it to a population level. Obviously more is better, but this myth about some sort of useless flu vaccine needs to be countered.

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    Nov 30th 2020, 8:07 PM

    @Rory Mac Daibhéid: Finally, and this is all I have time for because as I say there’s a misrepresentation of the facts with virtually every sentence you wrote, the evidence for vit D efficacy vs. Covid is not particularly convincing compared to early vaccine data.

    What’s very strange is that you aren’t convinced by robust placebo controlled RCTs involving vaccines, yet mainly observational studies about vitamin D seem to have you on board. There are serious flaws with the methodology of a lot of these vit D trials and most of them aren’t randomised/placebo controlled, they just looked at trends. Strange how you’d ignore those limitations yet hold vaccines to a much higher standard of efficacy?

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    Nov 30th 2020, 8:10 PM

    @Rory Mac Daibhéid:
    The NYT above – the USA might be in competition with the much cheaper Oxford vaccines as with the similar Russian one.
    …..,…..

    Then there this:


    The 40-year-old trial participant, who received the vaccine shots on Oct. 1 at a trial site in Chennai, India, said he experienced acute “neurological and psychological” side effects after he received the vaccine. He is seeking 50 million rupees—around $676,000—in compensation. The man also called for the testing, manufacturing, and distribution of the AstraZeneca vaccine to be “stopped immediately”

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    Nov 30th 2020, 8:14 PM

    @Rory Mac Daibhéid:

    If they are rolled out in spring, how and when will we know if these vaccines work – last summer there were few deaths – the effectiveness of a vaccine may wane in the following winter!

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    Nov 30th 2020, 8:20 PM

    @▪️: I’m not misrepresenting anything.
    Thanks for reply.
    I feel Astra Zenca lied but look no point arguing over it as you can get into conspiracies and argue about stock markets signals like with Pfizer and market consolidation. No point though.

    I’ve never said flu vaccine was useless, I’m suggesting we should base our expectations on covid vaccine on Flu vaccine success.

    I fully expect a low efficacy (yes I kept using the wrong word) in covid vaccine in those that need it most, this is reality.

    To be optimistic if the efficacy in under 65s is high that can protect the older groups.

    On Vitamin D I think the science is extremely. Powerful on how it’s being studied for https://www.clinicaltrials.gov/ct2/results?cond=COVID-19&term=Vitamin+D&cntry=&state=&city=&dist=&Search=Search

    Vitamin D sufficiency is as important as vaccines, if they done both I’d imagine the lives potentially saved would exceed all expectations, only if they done both.
    And not ,400iu supplements but get everyone in the world to sufficiency levels over winter ,
    for clinical practice, a serum 25(OH)D concentration of more than 75 nmol/L (30 ng/mL) is necessary.

    Do this and vaccines and you’ll have a high efficacy.

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    Nov 30th 2020, 8:45 PM

    @Rory Mac Daibhéid: I honestly have no clue how you’ve read the story on the AZ/oxford trial mishap and have come to the conclusion that there was lying involved. You’re just brushing it off but it’s a big deal to say that they’ve lied, and you don’t seem to be providing any evidence for it. As for stock market manipulation, it’s mandatory for these companies to report findings as soon as they have them to reduce the risk of insider trading. Not sure if that’s what you were getting at?

    https://www.lexology.com/library/detail.aspx?g=f90570e9-5663-4033-a524-aa565f24136f

    More info on Market Abuse Regulation re: drug trials and disclosure in that link if you’re interested.

    “we should base our expectations on covid vaccine on Flu vaccine success”

    Why? The flu virus is a particularly difficult virus to vaccinate against. SARS-CoV-2 isn’t in the same family as flu. Why pick that one? MMR vaccines for example have extremely high efficacy. As do vaccines for many other viruses. It makes no sense to assume as a baseline that the Covid vaccines will have efficacy somewhere in the range of the flu vaccine, so why should that be our expectation?

    Now, re: the link you sent me about Vit D clinical trials… well. If you look at the list of trials that come up from that search, you see the vast majority of them haven’t been completed. When you filter out for completed trials, the majority haven’t posted results. The only ones (two studies) that have posted results aren’t even testing Vitamin D!

    This is exactly what I’m talking about; there is a serious lack of *good* data to back up the Vit D hypothesis as things stand, for sure it’s worth intensive study (as we can see, it’s in progress) but it’s totally nonsensical to say Vit D is more (or as) promising compared to the various vaccine trials.

    Agree with sufficiency levels being a good goal to strive for just in terms of general health, but the hype surrounding the Covid question is completely separate and I’ve not seen anything rock solid yet. There are plenty of trials underway, the sensible thing to do is wait and see what they come up with before going flying into mass Vit D prophylaxis for C-19.

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    Nov 30th 2020, 8:54 PM

    @Joeohah: if the vaccine is a success In older people that’s good enough for me.

    But the idea that healthy under 55s show success in a vaccine by having a asymptomatic cases is basically what covid does to someone with sufficient vitamin D and especially someone with common exposure to circulating non covid 19 coronaviruses but the numerous other similar viruses in circulation, cross immunity.

    I actually think the success of the vaccine wouldn’t be very clear.
    I think it will be similar to flu vaccine which doesn’t eradicate it.
    Flu seems to have not arrived in any large numbers this season yet though so that’s quite novel so far.
    It’s very difficult to prove a lot of things with covid.
    I heard they’re planning a direct infection study in the UK in January to find out what a ‘infectious dose’ is.
    Many unknowns and when the existing Immunity of volunteers is ignored and exposure we’ve no idea how efficacious a vaccine really is.
    I’d base the success on the lower rates of success of the flu vaccine which unfortunately fails to directly protect deaths in many of the most vunerable but indirectly less circulation and transmission is their Protection.

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    Nov 30th 2020, 9:15 PM

    @▪️: every expert in the world including Irish ones have said Vitamin D supplements will save lives especially over the winter, so we do need to rush it.
    Uk is ahead of the curve here.
    AstraZeneca manipulated and lied and they have been called out in the media over it.
    You can find the article.

    I’m correct in being skeptical.

    That’s doesn’t equate with not supporting it .
    I’m not interested in press releases and statements or tiny trials.
    The real trail hasn’t Started yet.
    Only then will we see if it’s just ‘as good’ as flu vaccine.
    Our strategies for society must assume this low level of success only not fantasies of eradication and defeat of the virus.

    I’m being skeptical of a vaccine for a respiratory illness similar to flu achieving immune response in mean age of Irish deaths 81 plus.

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    Dec 1st 2020, 2:28 AM

    @Rory Mac Daibhéid: No, they have tested the safety and effecinvess of the vaccines on older adults…

    Anderson, E.J., Rouphael, N.G., Widge, A.T., Jackson, L.A., Roberts, P.C., Makhene, M., Chappell, J.D., Denison, M.R., Stevens, L.J., Pruijssers, A.J. and McDermott, A.B., 2020. Safety and immunogenicity of SARS-CoV-2 mRNA-1273 vaccine in older adults. New England Journal of Medicine. https://www.nejm.org/doi/full/10.1056/NEJMoa2028436

    Ramasamy, M.N., Minassian, A.M., Ewer, K.J., Flaxman, A.L., Folegatti, P.M., Owens, D.R., Voysey, M., Aley, P.K., Angus, B., Babbage, G. and Belij-Rammerstorfer, S., 2020. Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial. The Lancet.

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    Dec 1st 2020, 9:45 AM

    @Rory Mac Daibhéid: I’m one of those ‘vulnerable’ people you refer to. I won’t go into details about my collection of conditions, comorbidities they call them, but suffice to say if i were to catch Covid-19 I’d be unlikely to survive. So, would I take the vaccine then? Yes, in a heartbeat.
    Think about that. Covid-19 will kill me, that’s a given. The vaccine is almost guarranteed to protect me, with no side effects so anyone like me would have to be an idiot not to take it. Tell me, what exactly is your qualification, what experiance do you have in the medical field, because I prefer to take my advice from the qualified experts.

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    Dec 1st 2020, 11:30 AM

    @Arch Angel: you might be confused, I’ve asked a question(a)
    I also gave an opinion.
    I’ve never suggesting someone doesn’t take the vaccine, When did I suggest that?
    I don’t believe it’s going to directly work on the immune system of those who covid kills, that’s not a popular thing to say but it’s my opinion.
    I think the vaccine will have to avoid these deaths by less Covid.

    I’d recommend everyone makes sure their vitamin D levels are over 30 also as that’s correlated with covid killing you.

    Hope that makes more sense.
    As for qualifications and medical Fields, are you trying to cancel a conversation? I don’t know about you but two of the posters in this thread made me feel more confident about the testing on older groups but just not the plus 80 age range.

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    Dec 1st 2020, 11:38 AM

    @David Jordan: thanks David.
    But that link confirms what I’m saying.
    “participants between the ages of 56 and 70 years at the 25-μg dose, which was followed by the ”
    They’re not testing the vaccine on those who covid has killed in Ireland, majority are over 80 with underlying conditions.
    That’s reality.
    I’ve seen zero evidence the vaccine will work in them .
    I’m not overly concerned the vaccine won’t be safe in under 55, average age of vaccine trials is 40!
    What’s the evidence a mean age of 40 can save a mean age of an 81 year old with underlying conditions from covid.
    I’d say none directly.
    Indirectly yes.
    That’s my issue , the data on who covid killed in Ireland is quite clear. And seeing as that’s the media obsession should the vaccine not be to save these people?

    My feeling is the vaccine will and be relatively safe on younger people but I’m not sure if these entire magic bullet of a vaccine for saving lives is going to be proven at all.
    That’s what the Stage 3 Trial are not evidence of much to me.
    7000 people 55-70 is nothing in comparison to the older population in Ireland alone.
    Let’s see what happens then with the real life data.

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    Dec 2nd 2020, 12:34 PM

    @Tricia G: the professor now says exactly what I’ve said.
    Hmmmn
    https://www.rte.ie/player/series/claire-byrne-live-e33/SI0000000325?epguid=IH000383153

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    Dec 2nd 2020, 12:35 PM

    @David Jordan: Professor backing up exactly what I’m saying
    https://www.rte.ie/player/series/claire-byrne-live-e33/SI0000000325?epguid=IH000383153

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    Dec 2nd 2020, 12:36 PM

    @▪️: oh look an actual Professor Saying exactly what I am saying, interesting when you’re backed up by the experts
    https://www.rte.ie/player/series/claire-byrne-live-e33/SI0000000325?epguid=IH000383153

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    Nov 30th 2020, 5:21 PM

    Probably like a game of bulldog,, don’t mind getting involved but rather start at the back..

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    Nov 30th 2020, 5:26 PM

    @Seymour business: Well, unless you’re a Frontline medical worker, elderly or with chronic underlying conditions you’ll probably be at the back. Which is where I’ll be too.

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    Nov 30th 2020, 7:50 PM

    If these vaccines are rolled out for the majority of people next year how will we know the these vaccines have worked – last summer there were few Covid death thus by next winter it’s probably that the vaccine will be less effective…..?

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    Nov 30th 2020, 8:12 PM

    @Joeohah: We’ll know because even after they roll out vaccines to the market they continue to recruit people for randomised controlled trials, so the data will get better and better on how effective they are (or aren’t).

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    Nov 30th 2020, 10:39 PM

    @▪️:
    People don’t get ill from SARS CoV2 in the summer that’s been proved, so again how will they know it’s the vaccine and not the summer increase in immunity and not the vaccine.

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